Compositions and serological methods including bovine serum albumin polymers
US4046871A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Apr 8, 1975 |
| Grant date | Sep 6, 1977 |
| Priority date | — |
| Expiry date | Apr 8, 1995 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/826
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
New serological albumin compositions are provided which have greater potentiating capabilities than existing compositions in agglutination reactions of the IgG class of immune globulins. The essential component is at least one covalently bonded serum albumin polymer. The novel polymers are those containing from two to about eight or more monomeric albumin units which are joined to each other through a covalent peptide bond. Serological compositions may be prepared by polymerization of a dilute aqueous albumin solution, quenching of the reaction, precipitation of the products as solids, dissolution of albumin solids with or without separation of polymers in physiological or isotonic solutions. The compositions are useful as diluents for reagent preparation and for titration media, and as antibody detecting media.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.