3-Carboalkoxy (or phenoxy) and 3-thiocarbo-(3-chloro-2-propenyl)-1,3,5,7-tetraazabicyclo(3.3.1)nonane and preparation
US4048166A · kind A · utility
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5Claims
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Key dates
| Filing date | Nov 11, 1976 |
| Grant date | Sep 13, 1977 |
| Priority date | — |
| Expiry date | Nov 11, 1996 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01N47/22
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## where X represents O or S and R represents C.sub.1-4 alkyl, phenyl or (C.sub.1-4 alkyl)phenyl. The compounds are prepared by reacting the ring-opened intermediate, obtained by reacting cis-1-(3-chloro-2-propenyl)-3,5,7-triaza-1-azoniatricyclo (3.3.1.1.sup.3,7) decane chloride with excess aqueous sodium hydroxide, with an equivalent amount of a corresponding halide formate or halide thioformate, ClC=X(OR), at about 0.degree. C in the presenceof a hydrogen chloride acceptor and using a non-nucleophilic organic solvent as reaction medium. The carbamate products have antimicrobial utility.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.