N,N-disubstituted derivatives of 3-carboxamide or 3-thiocarboxamide-7-(3-chloro-2-propenyl)-1,3,5,7-tetraazabicyclo(3.3.1) nonane and preparation II
US4048167A · kind A · utility
8Cited by
1References
7Claims
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Key dates
| Filing date | Nov 11, 1976 |
| Grant date | Sep 13, 1977 |
| Priority date | — |
| Expiry date | Nov 11, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## where X represents O or S and R.sub.1 and R.sub.2 each represents lower alkyl, phenyl or (lower alkyl)phenyl. The compounds are prepared by reacting the ring-opened intermediate (obtained by reacting cis-1-(3-chloro-2-propenyl)-3,5,7-triaza-1-azoniatricyclo(3.3.1.1.sup.3,7) decane chloride with excess aqueous sodium hydroxide) with an equivalent amount of a corresponding carbamoyl halide or thiocarbamoyl halide or at a low temperature to give the indicated tetrasubstituted urea or thiourea product. The compounds have antimicrobial utility.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.