Certain 2-substituted 4-phenylquinoline-4-ols
US4048177A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 7, 1976 |
| Grant date | Sep 13, 1977 |
| Priority date | — |
| Expiry date | Jan 7, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to quinoline derivatives of the formula (I) ##STR1## and the pharmaceutically acceptable acid addition salts of those compounds capable of forming acid addition salts. In formula (I), R.sup.1 and R.sup.2 which may be the same of different each represent hydrogen, lower alkyl, lower alkoxy, trifluoromethyl or halogen, R.sup.3 and R.sup.4 which may be the same or different each represent lower alkyl and X represents hydroxy, halogen, hydrazino, or a radical of formula -NR.sup.5 R.sup.6 where R.sup.5 and R.sup.6 which may be the same or different each represent hydrogen or lower alkyl or R.sup.5 and R.sup.6 together with the nitrogen atom to which they are both attached represent a saturated heterocyclic ring containing 5 to 7 ring atoms. The compounds possess hypotensive activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.