Disubstituted azabicycloalkanes

US4048321A · kind A · utility

Assignee

• Science Union et Cie · FR

Inventors

• Laszlo Beregi · La Roche-sur-Yon, FR
• Pierre Hugon · Rueil-Malmaison, FR
• Xavier Pascaud · Paris, FR
• Jean-Claude Poignant · Les Ulis, FR

Key dates

• Filing date: May 13, 1976
• Grant date: Sep 13, 1977
• Expiry date: May 13, 1996

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/44
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disubstituted azabicycloalkanes of the formula ##STR1## wherein: N IS 0, 1 OR 2 PA1 R is saturated or unsaturated straight or branched (C.sub.1 -C.sub.5) aliphatic hydrocarbon, and PA1 X.sub.1, x.sub.2, x.sub.3, x.sub.4, x.sub.5, which are the same or different, are hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, trifluoromethyl, nitro, amino or sulfamoyl. These compounds are used as medicine especially in the treatment of gastroduodenal ulcers, gastric hypersecretion, nauseous syndromes of central origin and hypertension.