Ibuprofen p-hydroxyphenylurea ester
US4049700A · kind A · utility
7Cited by
1References
1Claims
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Assignee
Inventor
Key dates
| Filing date | Jun 17, 1976 |
| Grant date | Sep 20, 1977 |
| Priority date | — |
| Expiry date | Jun 17, 1996 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Ibuprofen p-hydroxyphenylurea ester having the formula II: ##STR1## was prepared from the free acid, ibuprofen [.+-.2-(p-isobutylphenyl)propionic acid](I). The ester II above has the anti-inflammatory activity of the free acid, but in contradistinction to it, it has a pleasant taste, suitable for oral administration such as uncoated tablets, suspensions or syrups, for the treatment of inflammatory conditions, particularly arthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.