Antiviral 2-amino-5-[1-(indol-3-yl)alkyl]-2-thiazolin-4-ones
US4049816A · kind A · utility
11Cited by
1References
24Claims
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Inventors
Key dates
| Filing date | Mar 15, 1976 |
| Grant date | Sep 20, 1977 |
| Priority date | — |
| Expiry date | Mar 15, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Thiazolinone analogues of indolmycin having anti-viral activity as well as a degree of antibacterial and antimycoplasmal activity in contrast to the known indolmycin which has only some antibacterial activity. Tautomers and a single enantiomer or mixture of enantiomers are included. Intermediates are described which are cyclized to produce the active antiviral substances. Suitable dosage forms and amounts are set forth and various routes of administration included including administration to the respiratory tract as by insufflation or inhalation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.