Patent · US Expired

Thiazole derivatives and processes for preparing the same

US4052407A · kind A · utility

3Cited by
1References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 14, 1975
Grant dateOct 4, 1977
Priority date
Expiry dateMay 14, 1995

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D277/30
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel thiazole derivatives of the formula ##STR1## wherein R.sub.1 and R.sub.2 are hydrogen or methyl, R.sub.3 is oxo, hydroxyl or acetoxy, have prostaglandin side chains and have an action that is more selective than that of natural prostaglandins. They inhibit the activity of enzymes inducing the decomposition of prostaglandins in the organism and thus they increase the endogenous level of prostaglandins. Various novel methods are provided for their production.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.