Method of acylation of phloroglucinol
US4053517A · kind A · utility
3Cited by
3References
23Claims
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Key dates
| Filing date | May 5, 1976 |
| Grant date | Oct 11, 1977 |
| Priority date | — |
| Expiry date | May 5, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C45/71
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of acylation of phloroglucinol in the presence of a Friedel Crafts catalyst which is effected in the presence of nitromethane and dichloromethane so as to produce an acylphloroglucinol. The acylphloroglucinol is reacted with a compound selected from .gamma.,.gamma.-dimethyl allyl bromide and 2-methyl-but-3-ene-2-ol in the presence of a weak Lewis acid and in an organic solvent to produce a 4-desoxyhumulone which is then oxidized to produce a corresponding humulone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.