Thiazole alkanoic acids, hypolipemiant compositions containing them and methods of inducing hypolipemic activity utilizing them
US4053618A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 2, 1976 |
| Grant date | Oct 11, 1977 |
| Priority date | — |
| Expiry date | Feb 2, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel thiazole derivatives of the formula ##STR1## wherein R is alkyl of 1 to 5 carbon atoms, Z is selected from the group consisting of --CH.dbd.CH--, --CH.dbd.CH--CH.dbd.CH-- and (CH.sub.2).sub.n --, n is an integer from 1 to 6 and R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, --NH.sub.4 and alkali metal, alkaline earth metal and aluminum cations and the non-toxic, pharmaceutically acceptable acid addition salts thereof which have antilipolytic activity and are useful intermediates and their preparation and intermediates produced therein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.