Patent · US Expired

Thiazole alkanoic acids, hypolipemiant compositions containing them and methods of inducing hypolipemic activity utilizing them

US4053618A · kind A · utility

0Cited by
3References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 2, 1976
Grant dateOct 11, 1977
Priority date
Expiry dateFeb 2, 1996

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D277/30
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel thiazole derivatives of the formula ##STR1## wherein R is alkyl of 1 to 5 carbon atoms, Z is selected from the group consisting of --CH.dbd.CH--, --CH.dbd.CH--CH.dbd.CH-- and (CH.sub.2).sub.n --, n is an integer from 1 to 6 and R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, --NH.sub.4 and alkali metal, alkaline earth metal and aluminum cations and the non-toxic, pharmaceutically acceptable acid addition salts thereof which have antilipolytic activity and are useful intermediates and their preparation and intermediates produced therein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.