1-[2-(.beta.Naphthyloxy)ethyl]-3-methylpyrazolone-(5) and antithrombotic and antithrombolytic compositions and methods utilizing them
US4053621A · kind A · utility
5Cited by
26References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 2, 1975 |
| Grant date | Oct 11, 1977 |
| Priority date | — |
| Expiry date | Jun 2, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
1-[2-(.beta.-Naphthyloxy)ethyl]-3-methylpyrazolone-(5) and its salts are useful in the treatment and prophylaxis of thrombotic conditions. The compound is prepared through the reaction of 2-(.beta.-naphthyloxy)ethylhydrazine with either an acetoacetate or an ester of tetrolic acid, or through the condensation of 3-methylpyrazolinone-(5) with a derivative of 2-(.beta.-naphthyloxy)ethane, optionally with subsequent salt formation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.