Certain 4-phenoxy(or phenylthio)-3-n-acylated-sulfonamido-pyridines

US4055650A · kind A · utility

Assignee

• A. Christiaens Societe Anonyme · BE

Inventors

• Jacques Delarge · Dolembreux, BE
• Charles L. Lapiere · Tongeren, BE
• Andre H. Georges · Ottignies, BE

Key dates

• Filing date: Jun 9, 1976
• Grant date: Oct 25, 1977
• Expiry date: Jun 9, 1996

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/71
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to new derivatives of pyridine having hypo-uricemic or hypolipemic properties. The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which X represents an oxy or thio group, R.sub.1 represents hydrogen, a group of the formula R.sub.3 NHCO (II), wherein R.sub.3 represents a C.sub.1 -C.sub.4 -alkyl, cycloalkyl or possibly substituted phenyl group, or a group of the formula R.sub.4 --CO (III) in which R.sub.4 represents a C.sub.1- C.sub.4 -alkyl group or a possibly substituted phenyl group, and R', R" and R'" represent each a possible substituent selected from the group comprising the halogens, the trifluoromethyl and the C.sub.1- C.sub.4 alkyl groups.