Patent · US Expired

9-(2-O-Acyl-.beta.-D-arabinofuranosyl)-adenine compounds and method for their production

US4055718A · kind A · utility

5Cited by
1References
4Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMay 17, 1976
Grant dateOct 25, 1977
Priority date
Expiry dateMay 17, 1996

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P19/40
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

9-(2-O-Acyl-.beta.-D-arabinofuranosyl)adenine compounds and their production by enzymatic removal of the 3-O-acyl and 5-O-acyl groups of a 9-(2,3-di-O-acyl-.beta.-D-arabinofuranosyl)adenine compound or a 9-(2,3,5-tri-O-acyl-.beta.-D-arabinofuranosyl)adenine compound. The monoester compounds are useful as antiviral agents. The compounds are watersoluble and lipophilic, thereby being adaptable to a wide variety of pharmaceutical formulations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.