Dibenzopyrimidoazepines
US4056529A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 8, 1976 |
| Grant date | Nov 1, 1977 |
| Priority date | — |
| Expiry date | Jan 8, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to dibenzopyrimidoazepines of the formula (I) ##STR1## and their acid addition and quaternary ammonium salts. In formula (I) R.sup.1 and R.sup.2 each represent hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl and X represents two hydrogen atoms, an oxo group, a protected oxo group or an oximino group. The compounds in which X represents two hydrogen atoms, an oxo group or an oximino group possess hypoglycaemic activity. The compound in which X represents a protected oxo group are intermediates for preparing the compounds in which X is an oxo group. The dibenzopyrimidoazepines may be prepared by cyclising or cyclodehydrating novel morphanthridine derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.