Pharmaceutical composition containing benzofuran derivative
US4056626A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 27, 1976 |
| Grant date | Nov 1, 1977 |
| Priority date | — |
| Expiry date | Feb 27, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/86
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A pharmaceutical composition containing as the essential active ingredient a benzofuran derivative of the formula: ##STR1## wherein A is --COR', ##STR2## or ethyl group; B is hydrogen atom when A is --COR' ##STR3## or --COR" substituted at the 3 or 4 position of the benzofuran nucleus when A is ethyl; R is an alkyl group having 1 to 5 carbon atoms; R' is an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 3 carbon atoms or phenyl group; R" is an alkyl group having 1 to 4 carbon atoms, phenyl or phenylalkyl group wherein the alkyl moiety has 1 to 2 carbon atoms; and the substituted propoxy group is at the 3, 4, 5, 6 or 7 position of the benzofuran nucleus; or a pharmaceutically acceptable acid addition salt thereof in admixture with a pharmaceutically acceptable carrier. The pharmaceutical composition possesses a superior .beta.-adrenergic blocking activity and local anesthetic activity, and is useful for the prevention and treatment of heart diseases, hypertension and hyperthyroidism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.