Hydrogenation of cyclic unsaturated compounds
US4058572A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 6, 1975 |
| Grant date | Nov 15, 1977 |
| Priority date | — |
| Expiry date | May 6, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C35/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
In a process for hydrogenation, with elemental hydrogen gas in the presence of a hydrogenation catalyst, of a cyclic unsaturated compound having an hydroxyl group projecting from an asymmetric center of the ring and an olefinic carbon-to-carbon double bond which when saturated in the hydrogenation process creates an additional asymmetric center in the ring, the improvement for obtaining increased stereoselectivity by increasing the addition of said hydrogen to that side of the olefin bond on the same side of the compound molecule as said hydroxyl group, comprising: conducting said hydrogenation with a nickel hydrogenation catalyst that has a substantial fraction of its reactive surfaces inactivated. The invention is particularly applicable to the hydrogenation of d-trans-piperitol to d-isomenthol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.