Extraction of N-blocked amino acids from aqueous media
US4059573A · kind A · utility
3Cited by
4References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 30, 1976 |
| Grant date | Nov 22, 1977 |
| Priority date | — |
| Expiry date | Mar 30, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D499/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
N-blocked amino acids, particularly derived from natural sources such as fermentation liquors, are extractively esterified from aqueous media by treatment of the aqueous solution with a diazoalkane, e.g. diphenyldiazomethane, in the presence of a water-immiscible organic solvent. Useful applications of the process include the extractive esterification of N-blocked derivatives of cephalosporin C and desacetyl cephalosporin C from fermentation broths.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.