Substituted 4-hydroxyphenyl guanidines
US4060554A · kind A · utility
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Key dates
| Filing date | Jan 25, 1977 |
| Grant date | Nov 29, 1977 |
| Priority date | — |
| Expiry date | Jan 25, 1997 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/155
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel aromatic guanidine compounds having the formula: ##STR1## wherein: R.sub.1 is hydroxyl, methyl or hydroxymethyl and R.sub.2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be activate as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.