Process for the preparation of a container closed under sterile conditions and containing lyophilized material

US4060911A · kind A · utility

Assignee

• Behringwerke Aktiengesellschaft · DE

Inventors

• Herbert Weiler · Gilching, DE
• Hans Schneider · Marburg, DE
• Wolfgang Von Janecek
• Ludwin Weyrich

Key dates

• Filing date: Aug 7, 1975
• Grant date: Dec 6, 1977
• Expiry date: Aug 7, 1995

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B67B3/24
• WIPO field: Handling
• WIPO sector: Mechanical engineering

Abstract

A process for the preparation of a container closed under sterile conditions and containing lyophilized material, which comprises PA1 1. filling the material to be lyophilized into a container, PA1 2. putting a rubber stopper and a closing cap loosely on the container, PA1 3. introducing the container with its contents into a lyophilization apparatus, PA1 4. lyophilizing the contents, PA1 5. within the lyophilization apparatus and in a single operation, pressing the rubber stopper deep into the container, at the same time pressing the closing cap onto the same, and PA1 6. removing the container closed under sterile conditions from the lyophilization apparatus.