Patent · US Expired

Somatostatin analogs and intermediates thereto

US4061626A · kind A · utility

7Cited by
7References
19Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 29, 1976
Grant dateDec 6, 1977
Priority date
Expiry dateApr 29, 1996

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/28
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The tetradecapeptides ##STR1## in which Y is Gly or D-Ala are described along with corresponding non-toxic pharmaceutically-acceptable acid addition salts as well as intermediates useful in the synthesis of the tetradecapeptides. The tetradecapeptide in which Y is Gly as well as its pharmaceutically acceptable acid addition salts exhibit as their principal activity the in vivo inhibition of the release of gastric acid. The tetradecapeptide in which Y is D-Ala as well as its pharmaceutically acceptable acid addition salts exhibit as their principal activity the in vivo stimulation of the release of growth hormone.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.