Process for the production of 2-amino-3-hydroxypyridines
US4061644A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 18, 1976 |
| Grant date | Dec 6, 1977 |
| Priority date | — |
| Expiry date | Jun 18, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/73
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for the production of 2-amino-3-hydroxypyridines of the formula ##STR1## wherein R.sub.1 and R.sub.2 independently of one another represent hydrogen or an alkyl group having 1 to 4 carbon atoms, wherein a furan-2-carboxylic acid of formula ##STR2## wherein R.sub.1 and R.sub.2 have the meaning given above, or a derivative thereof, for example a quaternary ammonium salt, an ester, an amide, a halogenide, an amidine salt, an iminoether salt or the nitrile, is reacted at a temperature of between 100.degree. and 300.degree. C in a solvent containing amide groups, in the presence of an acid catalyst, with ammonia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.