Selected quaternary ammonium salts of pilocarpine useful in reducing intraocular pressure in warm-blooded animals
US4061722A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Apr 26, 1976 |
| Grant date | Dec 6, 1977 |
| Priority date | — |
| Expiry date | Apr 26, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula: ##STR1## wherein R represents a member selected from the group consisting of a hydrogen atom, a C.sub.1 -C.sub.20 open chain or cyclo alkyl group, a C.sub.1 -C.sub.20 alkoxyalkyl group, a C.sub.1 -C.sub.20 alkanoyloxyalkyl group, a C.sub.1 -C.sub.20 haloalkyl group, a C.sub.1 -C.sub.20 carboxyalkyl group, a phenyl group, a naphthyl group and a substituted phenyl or naphthyl group, whose substituents are selected from the group consisting of a halogen atom, an O-C.sub.1 -C.sub.4 alkyl group, an O-C.sub.1 -C.sub.8 alkanoyl group, a nitro group, a carboxyl group, and a carboethoxy group; wherein R.sub.1 represents a C.sub.9 -C.sub.22 straight or branched alkyl group, a ##STR2## group, wherein R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are each selected from the group consisting of a hydrogen atom, a methyl group, or an ethyl group, and wherein R.sub.1 further represents a member selected from the group consisting of a C.sub.0 -C.sub.22 straight or branched alkyl ##STR3## group, wherein n in each occurrence and m represent an integer of from 0 to 22, and an ##STR4## group, wherein A represents a -(CH.sub.2 CH.sub.2 O).sub.p group, wherein the p represents an intege…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.