Halogenated amino methyl adamantane derivatives
US4061774A · kind A · utility
5Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1975 |
| Grant date | Dec 6, 1977 |
| Priority date | — |
| Expiry date | Apr 9, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D303/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel 2-substituted-1-methylamino adamantanes of formula: ##STR1## where X is hydroxyl or halogeno, and R.sup.1, R.sup.2 and R.sup.3 are hydrogen or C.sub.1-4 alkyl or R.sup.2 and R.sup.3 together with the nitrogen form a heterocyclic ring, having anti-Parkinsonian activity, pharmaceutical formulations containing the active adamantanes and novel 4-protoadamantane spiro oxirane and 1,2-difunctionalized intermediates useful in the preparation of the final products of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.