Blood substitute based on hemoglobin
US4064118A · kind A · utility
53Cited by
3References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 8, 1976 |
| Grant date | Dec 20, 1977 |
| Priority date | — |
| Expiry date | Oct 8, 1996 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/105831
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A blood substitute or blood extender is prepared by chemically coupling hemoglobin with a polysaccharide material selected from dextran and hydroxyethyl starch, and having a molecular weight of from about 5,000 to about 2,000,000, to form a covalently bonded chemical complex. The complex has similar oxygen transporting abilities to hemoglobin, and has a much lower rate of renal excretion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.