Substituted nitrobenzophenone derivatives and a process for the preparation thereof
US4064121A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 12, 1975 |
| Grant date | Dec 20, 1977 |
| Priority date | — |
| Expiry date | Aug 12, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New compounds of the general formula (I), ##STR1## wherein R.sub.1 and R.sub.2 each stand for a saturated or unsaturated, straight-chained or branched alkyl group, an aralkyl group, a saturated or unsaturated cycloalkyl group or an aryl group, or PA1 R.sub.1 and R.sub.2 together with the adjacent nitrogen atom may form an optionally substituted heterocyclic group optionally containing a further oxygen or nitrogen hetero atom, But if R.sub.1 stands for methyl, R.sub.2 may only stand for a group other than methyl, are prepared by reacting a compound of the general formula ##STR2## wherein X stands for halogen, with a secondary amine of the general formula (III), EQU r.sub.1 --nh--r.sub.2 (iii) wherein R.sub.1 and R.sub.2 each have the same meanings as defined above. The new compounds of the general formula (I), as well as their pharmaceutical acceptable acid addition salts or quaternary ammonium salts are active primarily in the induction of liver microsomal enzyme, but they also possess antipyretic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.