Certain thiazole-5-carboxamide compounds
US4064135A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 19, 1976 |
| Grant date | Dec 20, 1977 |
| Priority date | — |
| Expiry date | Jul 19, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/36
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Processes and intermediates for preparing 1-alkylamino-3-(5-substitutedaminocarbonylthiazol-2-yloxy)-2-propanols and 5-(5-substitutedaminocarbonylthiazol-2-yloxymethylene)-N-alkyloxazolidine and 2-substituted oxazolidine derivatives thereof and intermediates therefore. The present processes, and intermediates, reduce the number of transformations necessary to produce these products as compared with the prior processes. The products are useful to treat abnormal heart conditions and/or hypertension in mammals. The intermediates are 2-alkylsulfinyl-5-substitutedaminocarbonylthiazoles and 2-alkylsulfonyl-5-substitutedaminocarbonylthiazoles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.