N'-(Aminoacylaminophenyl) acetamidines

US4064270A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Hartmund Wollweber · Wuppertal, DE
• Ekkehard Niemers · Wuppertal, DE
• Hans Peter Schulz
• Herbert Thomas
• Peter Andrews · Wuppertal, DE

Key dates

• Filing date: Sep 13, 1974
• Grant date: Dec 20, 1977
• Expiry date: Sep 13, 1994

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A new class of N'-(aminoacylaminophenyl) acetamidines: ##STR1## in which R.sup.1 and R.sup.2 are the same or different and represent hydrogen, alkyl, aryl or the substituted derivatives thereof or, together with the nitrogen atom to which they are attached, an heterocyclic ring; and R.sup.3 is hydrogen, alkyl, aryl, aralkyl, or a heterocyclic moiety including the substituted derivatives thereof. The products have utility as anthelmintics. The products are obtained by treating a suitable amino-acid or a carbonyl-activated amino-acid, with the appropriate N'-(4-aminophenyl)-N,N-dimethylacetamidine. In addition, the products are obtained by treating a suitable N'-(haloacylaminophenylacetamidine with an appropriate amine.