9-OXO-15 .xi.-HYDROXY-20-ALKYLIDENEPROST-13(TRANS)-ENOIC ACID DERIVATIVES
US4064351A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 22, 1976 |
| Grant date | Dec 20, 1977 |
| Priority date | — |
| Expiry date | Dec 22, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/4015
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Prostanoic acid derivatives having the formula ##STR1## wherein A represents ethylene group or cis-vinylene group, R.sup.1 and R.sup.2 may be the same or different and each represents hydrogen atom or an alkyl group having 1-3 carbon atoms, R.sup.3 and R.sup.4 may be the same or different and each represents an alkyl group having 1-3 carbon atoms and R.sup.5 represents hydrogen atom or hydroxyl group and the pharmaceutically acceptable salts thereof and a process for the preparation thereof. The compounds are useful as anti-ulcerogenic or bronchodilating agents and may be prepared by oxidizing 9.xi.-hydroxy-15.xi.-protected-hydroxy-20-alkylideneprost-13(trans)-enoic acid derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.