Patent · US Expired

Intermediates for polycyclic quinoid antibiotics

US4070382A · kind A · utility

8Cited by
6References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 18, 1975
Grant dateJan 24, 1978
Priority date
Expiry dateNov 18, 1995

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C46/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There is provided a novel method of synthesizing certain tetracyclic quinones. In particular, there is provided a novel route to the synthesis of (.+-.)-7-deoxydaunomycinone and analogs thereof, which includes the provision of novel tri- and tetracyclic quinone intermediates. The -7-deoxydaunomycinone derived from naturally occurring daunomycin is a known compound, which is itself an intermediate in the preparation of the clinically accepted anti-tumor antibiotics daunomycine and its derivative adriamycin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.