Process for preparing an emulsion
US4073743A · kind A · utility
31Cited by
7References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 13, 1976 |
| Grant date | Feb 14, 1978 |
| Priority date | — |
| Expiry date | Aug 13, 1996 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01F2215/0481
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for preparing a highly stable water-in-oil type emulsion consisting of (a) a disperse aqueous phase; (b) a continuous oil phase containing isomannide monooleate emulsifier and a non-hydrated physiologically acceptable fatty acid metal salt. A particular use of the invention is the preparation of an emulsion adjuvant vaccine, wherein the vaccine is incorporated in the aqueous phase. The emulsion is prepared by mixing the aqueous and oil phases at a relatively low agitator speed, optionally cooling, increasing the speed of agitation to form an emulsion and optionally homogenizing the emulsion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.