Patent · US Expired

2-Amino-4-phenyl-2-imidazolines and salts thereof

US4073905A · kind A · utility

5Cited by

1References

8Claims

0Family size

Assignee

Boehringer Ingelheim GmbH · DE

Inventors

Werner Kummer · Ingelheim am Rhein, DE
Herbert Koppe · Ingelheim am Rhein, DE
Helmut Stahle
Walter Haarmann

Key dates

Filing date	Mar 9, 1977
Grant date	Feb 14, 1978
Priority date	—
Expiry date	Mar 9, 1997

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D233/48
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each hydrogen, chlorine, bromine or alkyl of 1 to 3 carbon atoms, PA1 A is alkylene of 1 to 5 carbon atoms, and PA1 R.sub.6 and R.sub.7, together with each other and the nitrogen atom to which they are attached, form a heterocycle selected from the group consisting of morpholino, piperazino or N'-dimethylphenyl-piperazino, and PA1 R.sub.5 is hydrogen, alkyl of 1 to 3 carbon atoms, hydroxyethyl, diethylamino-ethyl or furfuryl, Provided, however, that R.sub.1 and R.sub.2 are other than both hydrogen or both alkyl at the same time, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as hypotensives, platelet aggregation inhibitors and antiarrhythmics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.