Process for azoles (ring closure of nitro compounds)
US4074046A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Oct 14, 1976 |
| Grant date | Feb 14, 1978 |
| Priority date | — |
| Expiry date | Oct 14, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/68
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for preparing known classes of 2-substituted azoles (I) and N-acylazolinones (II) by reacting carbon monoxide at elevated temperature and pressure in the presence of a cocatalyst composition, of which 5% palladium on carbon with a Lewis acid such as ferric chloride is representative, with a nitrogenous compound (III): ##STR1## to form the products (usually in admixture): ##STR2## where R is alkyl, alkenyl, aralkyl, aryl, styrl or ##STR3## R.sub.1 and R.sub.2 are hydrogen, alkyl, alkoxy, aryl, halo or, when taken together on adjacent carbon atoms, -CH.dbd.CH-CH.dbd.CH-; R.sub.4 may be alkyl, alkenyl, aralkyl, aryl, styryl, ##STR4## X is oxygen, sulfur or imino, Y is alkylene, alkenylene or arylene; and Z is nitro, azo or azoxy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.