1-Substituted-4-(2-oxo-hexahydro-1-pyrimidinyl)-piperidine
US4075208A · kind A · utility
2Cited by
3References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 28, 1976 |
| Grant date | Feb 21, 1978 |
| Priority date | — |
| Expiry date | Jan 28, 1996 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/635
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Piperidines of the formula ##STR1## in which R.sub.1 stands for optionally substituted aryl, R.sub.2 for hydrogen, lower alkyl, lower alkenyl, acyl or .alpha.-aryl-lower alkyl, R.sub.3 for a free or substituted hydroxyl group, alk for lower alkylene which separates the two nitrogen atoms by 2 or 3 carbon atoms, R.sub.4 represents hydrogen or lower alkyl and n represents an integer from 1 to 4, and their salts as well as processes for their manufacture and pharmaceutical compositions comprising such compounds, and a process for lowering the blood pressure wherein such compositions are administered to a warm-blooded host.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.