3-Alkoxyisoquinolines for hypotensive and vasodilating effects
US4075344A · kind A · utility
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2References
3Claims
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Assignee
Inventors
Key dates
| Filing date | Dec 22, 1976 |
| Grant date | Feb 21, 1978 |
| Priority date | — |
| Expiry date | Dec 22, 1996 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/47
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New 2-substituted-3(2H)-isoquinolones and 2-substituted-3-alkoxyisoquinolines are disclosed. They are orally active hypotensives and peripheral vasodilators with an extended duration of action. Representative embodiments of this invention are 6,7-dimethoxy-2-methyl-1-veratryl-3(2H)-isoquinolone hydrochloride, 2-allyl-6,7-dimethoxy-2-veratryl-3(2H)-isoquinolone hydrochloride, 2-cyclopropyl-6,7-dimethoxy-1-3(2H)-isoquinolone hydrochloride, 2-amino-6,7-dimethoxy-1-veratryl-3(2H)-isoquinolone hydrochloride and 3-ethoxy-6,7-dimethoxy-1-veratrylisoquinoline.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.