Substituted 3-(2-pyridinyl)-4(1H)-quinolinone N-oxides
US4076716A · kind A · utility
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4Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 25, 1976 |
| Grant date | Feb 28, 1978 |
| Priority date | — |
| Expiry date | Jun 25, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substituted 3-(2-pyridinyl)-4(1H)-quinolinone N-oxides having the formula I: ##STR1## wherein R.sub.1 is hydrogen, halogen, lower alkyl, hydroxy or alkoxy; R.sub.2 is hydrogen or lower alkyl; R.sub.3 is hydrogen or --CH.sub.2 OH; the dotted line indicates the possible presence of a double bond at the 2,3-position of the quinoline ring; the pharmaceutically acceptable acid addition salts thereof; and a process for the preparation thereof, are described. The compounds of the invention are useful for the treatment of hyperacidity and for the prevention of allergic and asthmatic reactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.