Patent · US Expired

Thieno-pyridine derivatives and therapeutic composition containing same

US4076819A · kind A · utility

26Cited by
1References
4Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 14, 1976
Grant dateFeb 28, 1978
Priority date
Expiry dateApr 14, 1996

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to thieno-pyridine derivatives having the formula: ##STR1## in which R.sub.1 is hydrogen or alkyl having 1-6 carbon atoms; R.sub.2 is hydrogen or acetyl or lower alkylcarbamoyl and R.sub.3 is methyl, nitrobenzyl, chlorobenzyl, methoxybenzyl, chlorobenzoyl, trimethoxybenzoyl, pyrrolidinoacetyl, p.toluene-sulfonyl, phenylcarbamoyl, phenylthiocarbamoyl, 3-oxo-butyl, lower alkyl-carbamoyloxy, phenethyl, dichloroacetyl, 2-chlorophenoxy-2-methyl-propionyl or chlorophenyl-carbamoyl, and their pharmaceutically acceptable acid addition salts. Said derivatives have useful anti-inflammatory properties and inhibiting effects on blood plate aggregation which make them therapeutically valuable.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.