Process for the production of 3-hydroxy-1,2,4-triazole derivatives
US4076938A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 22, 1977 |
| Grant date | Feb 28, 1978 |
| Priority date | — |
| Expiry date | Mar 22, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D249/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for the production of 3-hydroxy-1,2,4-triazole derivatives of the formula I ##STR1## wherein R.sub.1 represents an alkyl or cycloalkyl group, R.sub.2 denotes an alkyl, cycloalkyl, alkenyl, alkynyl or an optionally substituted benzyl group and X stands for oxygen, sulphur or a group <N--R.sub.3, wherein R.sub.3 denotes an alkyl, alkenyl or alkynyl group, or together with radical R.sub.2 and the adjacent nitrogen atom it denotes a pyrrolidino or morpholino group, wherein a 2-R.sub.1 -hydrazinecarboxylic acid ester is reacted with cyanogen chloride to form the corresponding 2-R.sub.1 -2-cyanohydrazinecarboxylic acid ester which is subsequently cyclized under alkaline conditions in the presence of a compound R.sub.2 XH.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.