Process using alkali fusion for decyanation of tert.-nitriles
US4079061A · kind A · utility
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10Claims
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Key dates
| Filing date | Jun 21, 1976 |
| Grant date | Mar 14, 1978 |
| Priority date | — |
| Expiry date | Jun 21, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An improvement in the decyanation of tertiary nitriles comprises the alkali fusion of the nitriles. Exemplary are the preparation of chlorpheniramine and brompheniramine by heating the respective nitriles in liquid sodium or potassium hydroxide at from 100.degree.-200.degree..
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.