1,2,4,5-Tetrahydro-3H-2-benzazepin-3-ones
US4080449A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 27, 1977 |
| Grant date | Mar 21, 1978 |
| Priority date | — |
| Expiry date | Jul 27, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C57/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New physiologically active 1,2,4,5-tetrahydro-3H-2-benzazepin-3-ones having the general formula ##STR1## wherein R.sub.1 is hydrogen or phenyl, R.sub.2 is hydrogen, alkyl, C.sub.3 -C.sub.6 -alkenyl, C.sub.1 -C.sub.4 -acyl, hydroxyalkyl, alkoxyalkyl, mono- or dialkylaminoalkyl, cyanoalkyl, alkoxyacetyl, carbamoylalkyl, acetamido-C.sub.2 -C.sub.5 -alkyl, alkoxycarbonylalkyl or (tetrahydro-2H-pyran-2-yloxy)alkyl, the alkyl and the alkoxy radicals having 1 to 5 carbon atoms, R.sub.4 is hydrogen or C.sub.1 -C.sub.4 -alkyl, R.sub.5 is hydrogen, C.sub.1 -C.sub.4 -alkyl or phenyl, R.sub.7 is hydrogen, halogen or C.sub.1 -C.sub.4 -alkoxy and R.sub.8 is hydrogen, halogen or C.sub.1 -C.sub.4 -alkyl, at least one of the symbols R.sub.1 to R.sub.8 being other hydrogen, processes for the preparation thereof and pharmaceutical compositions containing the same. In particular, the compounds of this invention are useful in the treatment of memory disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.