Patent · US Expired

Diacylapomorphines

US4080456A · kind A · utility

5Cited by

2References

13Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Dieter Seidelmann · Berlin, DE
Ralph Schmiechen · Berlin, DE
Reinhard Horowski
Wolfgang Kehr
Dieter Palenschat
Gert Paschelke

Key dates

Filing date	Nov 20, 1975
Grant date	Mar 21, 1978
Priority date	—
Expiry date	Nov 20, 1995

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D221/18
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Diacylapomorphines of the formula ##STR1## wherein R.sub.1 and R.sub.2 are both acyl of 1-17 carbons are symptomatically effective agents in the treatment of motor disorders of the type associated with a dopamine deficiency of the extrapyramidal system of the central nervous system, e.g. Parkinson's disease. Pharmaceutical compositions containing these compounds as an active ingredient are described, as well as new compunds of the above formula wherein R.sub.1 and R.sub.2 are formyl or acyl of 3-17 carbon atoms.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.