Preparation of D, L-pantolactone
US4082775A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 1, 1976 |
| Grant date | Apr 4, 1978 |
| Priority date | — |
| Expiry date | Jul 1, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/33
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a method for the synthesis of D, L-pantolactone by the reaction of (1) of hydroxypivaldehyde with hydrocyanic acid produced in situ followed by (2) hydrolysis of the cyanohydrin obtained. The pantolactone may then be separated from the reaction mixture. Each of the reactions (1) and (2) are conducted under closely controlled conditions of concentration, temperature, pH and time and, by virtue of these conditions, a yield exceeding 90% may be obtained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.