Detection and estimation of microquantities of alkylating agents
US4083692A · kind A · utility
9Cited by
7References
5Claims
0Family size
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Key dates
| Filing date | Jun 4, 1970 |
| Grant date | Apr 11, 1978 |
| Priority date | — |
| Expiry date | Jun 4, 1990 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/163333
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method comprising an unknown solution adding an organophosphorus thio a salt solution for sufficient time to form compounds having anticholinesterase activity in the reaction solution, contacting the reaction solution with a cholinesterase supported on a suitable substrate, adding indoxyl acetate and observing a non-color or blue color change in the substrate; the absence of color indicates the formation of compounds with anticholinesterase activity and the blue color of the substrate indicating that there was no formation of compounds with anticholinesterase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.