Patent · US Expired

Process

US4083857A · kind A · utility

2Cited by
1References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 31, 1976
Grant dateApr 11, 1978
Priority date
Expiry dateMar 31, 1996

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/16
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There is provided a process for the preparation of coumarin derivatives of the formula: ##STR1## (wherein R represents substituted or unsubstituted alkyl, aryl or aralkyl, R.sup.1 represents alkanoyl, and the hydroxy and R.sup.1 substituents are ortho to one another) in which a hydroxy-substituted coumarin of the formula: ##STR2## is acylated in the presence of a Friedel-Crafts catalyst. The compounds of formula I are intermediates in the preparation of certain pharmaceutically-active chromones.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.