Apparatus for continuous disintegration of cells of microorganisms
US4084757A · kind A · utility
Inventors
Key dates
| Filing date | Aug 5, 1976 |
| Grant date | Apr 18, 1978 |
| Priority date | — |
| Expiry date | Aug 5, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N1/066
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
To effect disintegration of cells of microorganisms such as yeast, bacteria, and fungi, a suspension of cells is presaturated with a compressed gas and then passed through one or more disintegration units containing a plate valve seat and valve member urged toward each other. The disintegration unit can be attached to a mechanical vibrator-shaker. At the inlet of said disintegration unit there are two thick-wall vessels, i.e. a mixing vessel to effect intermixing of the suspension and compressed gas and a homogenizing vessel to maintain the suspension under pressure. When the suspension is passed through a throttling slit formed between the valve seat and valve member, cell shells are intensively broken due to the internal pressure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.