Patent · US Expired

Process for obtaining insulin like active substances

US4085204A · kind A · utility

6Cited by

0References

8Claims

0Family size

Assignee

Helmut Mittenzwei

Inventors

Adolf Wacker · Neu-Isenburg, DE
Dorthe Wacker · Neu-Isenburg, DE
Klaus Pohler · Wiesbaden, DE
Hellmut Mittenzwei

Key dates

Filing date	Dec 9, 1976
Grant date	Apr 18, 1978
Priority date	—
Expiry date	Dec 9, 1996

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/83
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention concerns a novel process for obtaining insulin-like active substances from blood or a blood component of a warm-blooded animal, which comprises the steps of pre-treating the blood or blood component by adjusting the pH thereof to a value of from 2 to 4 or of from 8 to 10, incubating the pre-treated blood at a temperature of from about 15.degree. to about 40.degree. C for a period of at least four hours, cooling the incubated blood to a temperature of less than 10.degree. C, and recovering from the treated blood after neutralization organic peptide substances having a molecular weight of from about 1000 to about 5000, and an insulin-like activity of from about 14 to about 40 .mu.U/mg solid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.