Lowering blood pressure with new L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptides

US4087520A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Franz-Josef Braun · Rimbach, DE
• Kurt Stach
• by Werner Plattner, administrator · Linz, AT
• Max Thiel
• Gisbert Sponer · Hemsbach, DE
• Karl Dietmann

Key dates

• Filing date: Mar 9, 1976
• Grant date: May 2, 1978
• Expiry date: Mar 9, 1996

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/80
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptide of the formula ##STR1## wherein A is an alkylene radical which can be substituted by a hydroxyl group or by a phenyl radical which optionally carries at least one hydroxyl group, and PA1 R is a hydrogen atom or a lower alkyl radical or a glycyl or alanyl radical, Or a pharmacologically compatible salt thereof. These compounds are outstanding in lowering blood pressure.