5-Methyl-isoxazole-4-carboxylic acid anilides
US4087535A · kind A · utility
33Cited by
2References
24Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 3, 1976 |
| Grant date | May 2, 1978 |
| Priority date | — |
| Expiry date | Jun 3, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D261/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 5-methyl-isoxazole-4-carboxylic acid anilide is prepared by heating an acetoacetic acid anilide with an orthoformic acid ester and a carboxylic acid anhydride, isolating the resulting 2-alkoxymethylene-acetoacetic acid anilide and then treating it with hydroxylamine in an organic solvent. The compounds of the invention have anti-inflammatory and analgetic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.