Production of macrospherical particles for anti-perspirants and the like
US4089120A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 23, 1976 |
| Grant date | May 16, 1978 |
| Priority date | — |
| Expiry date | Sep 23, 1996 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S159/27
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process and apparatus are provided for making hollow macrospherical particles. The particles themselves are particularly adapted for use as anti-perspirants. The particles have a diameter between about 10 and 74 microns, preferably predominating between 15 and 44 microns, and a greater than unit density. As such, they are not subject to deep lung penetration. The process for producing the particles comprises providing a solution containing the materials from which the particles are made, diffusing the solution through small pores by centrifugal force such that the resulting hollow particles have a diameter greater than the pore diameter, and drying the solution droplets in a stream of heated air. The apparatus for producing the macrospherical particles comprises a centrifugal atomizer having a porous sintered metal filter ring which is rotated inside a spray drying chamber. The filter is treated to produce hollow macrospheres having substantially smooth outer walls of such thickness that they can withstand normal shipment and handling without significant fragmentation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.