Long-acting xanthine bronchodilators and antiallergy agents
US4089959A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Mar 31, 1976 |
| Grant date | May 16, 1978 |
| Priority date | — |
| Expiry date | Mar 31, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Prolonged bronchodilation and prolonged inhibition of allergic mediator release in mammals are produced by administering an effective amount of a substituted xanthine compound having the formula: ##STR1## wherein: R.sub.1 = methyl PA1 R.sub.3 = c.sub.4 -c.sub.7 alkyl, C.sub.4 -C.sub.7 cycloalkylalkyl C.sub.4 -C.sub.7 alkenyl, C.sub.4 -C.sub.7 alkynyl, or C.sub.4 -C.sub.7 cycloalkyl PA1 R.sub.8 = c.sub.1 -c.sub.2 alkyl These compounds are useful in the treatment of bronchial asthma and other bronchospastic and allergic diseases. The compounds are also novel. The bronchodilator and antiallergy agents may be administered in the form of tablets, capsules, aerosols, solutions, suspensions or suppositories.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.