Production of tertiary phosphine oxides

US4091012A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Hartfrid Vollmer
• Georg Elsner · Hürth, DE
• Bernd Lippsmeier
• Klaus Hestermann · Lechenich, DE

Key dates

• Filing date: Mar 24, 1977
• Grant date: May 23, 1978
• Expiry date: Mar 24, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/5304
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Production of tertiary phosphine oxides which contain nitrile groups and correspond to the following general formula I: ##STR1## in which R.sup.1 and R.sub.2 each stand for a straight or branched, identical or different alkyl, cycloalkyl, aryl, alkylaryl or aralkyl group having 1 to 18 carbon atoms, and in which R.sup.1 or R.sub.2 may be identical with R, which stands for a radical of the following general formula II: ##STR2## in which R.sup.3 and R.sup.4 each stand for a straight or branched, identical or different alkyl, cycloalkyl, aryl, alkylaryl or aralkyl group having 1 to 18 carbon atoms, and/or hydrogen atoms. The tertiary phosphine oxides are made by reacting a phosphine of the following general formula III: ##STR3## in which R.sup.5 has the same meaning as R.sup.3 and R.sup.6 has the same meaning as R.sup.4 but is no hydrogen, with an .alpha.,.beta.-unsaturated nitrile of the following general formula IV: ##STR4## in which R.sup.3 and R.sup.4 have the meanings given above. The reaction is effected in a single stage in the presence of water or a water-solvent mixture and the above formula I compounds are separated from the reaction product.